Human Chromosome 7 Physical Map: References












Human Chromosome 7 Mapping and Sequencing Genome Technology Branch DIR Projects

Table 3
Characteristics of Different Sources of Mapped Chromosome 7 STSs

YAC-Based Connectivity to Genethon Genetic Markers^c

STS Source^a Mapped to YAC Contig^b Same YAC Same Contig No Connection Negative YAC Screen^d

Random 568 (26%) 500 58 10 6

YAC Insert Ends 790 (37%) 690 80 20 0

Genetic Markers 438 (20%) 157 17 4 4

Genes/ESTs 354 (17%) 293 43 18 13

Total 2150 1640 (87%) 198 (10%) 52 (3%) 23

^aThe chromosome 7-specific STSs can be broadly classified into four major categories: those derived from sequences corresponding to random segments of chromosome 7 DNA [e.g., isolated by flow-sorting, subcloning, or Alu-PCR amplification of human DNA from chromosome 7-containing monochromosomal hybrid cell lines (Green et al. 1991a; Green 1993; Bouffard et al. 1997)], YAC insert ends, genetic (microsatellite) markers, and genes and ESTs.

^bNumber (and relative percentage) of STSs mapped to the YAC contigs listed in Table 1, indicated for each STS source.

^cYAC-based physical connectivity between the mapped chromosome 7 STSs and Genethon genetic markers is indicated. A B total of 1890 chromosome 7 STSs (2150 mapped STSs minus the 260 mapped Genethon genetic markers) were analyzed for their YAC-based connection to one or more of the 260 Genethon genetic markers localized on the contigs listed in Table 1. Indicated are the numbers of STSs from each source connected to a Genethon genetic marker(s) by the same YAC(s) or same YAC contig (but not the same YAC), as well as those with no YAC-based connection to a Genethon genetic marker (Green et al. 1994). The total (and relative percentage) for each of the three indicated categories is also provided.

^dNumber of STSs for which no positive YAC could be identified, indicated for each STS source.

PREVIOUS Human Chromosome 7 Physical Map
NEXT

| NHGRI | DIR | Staff | Labs/Offices | Resources |
| News | Education | Search |

bioinformatics@nhgri.nih.gov