A Physical Map of Human Chromosome 7:
An Integrated YAC Contig Map with
Average STS Spacing of 79 kb

Title Page

Overview of Project

Mapping Reagents

Integration with Genetic, RH, and Cytogenetic Maps

General Features of Assembled YAC Contigs and STS Maps

Unanchored Contigs

Gaps on Contig Map

Apparent False-Negative and False-Positive Data

Complex Chromosomal Regions

Indices of Map Completion

Relationship Between Genetic and Physical Distance

Data Dissemination

Methods

STS Order

Theoretical Considerations

Comparison to Other Chromosome 7 Physical Maps

Comparison to Physical Maps of Other Human Chromosomes

Problems Encountered

Utility of Map

Chromosome 7 STSs

YAC Clones

Strategy for Map Construction

Table 1	YAC Contigs Constituting the Human Chromosome 7 Physical Map
Table 2	World Wide Web Sites Containing Chromosome 7 Mapping Data
Table 3	Characteristics of Different Sources of Mapped Chromosome 7 STSs
Table 4	Characteristics of Different Sources of Mapped Chromosome 7 YACs

Figures

Figure 1	Distribution of STSs on the chromosome 7 YAC contig map, Genethon genetic map, and/or RH map.
Figure 2	Physical location of markers on the chromosome 7 Genethon genetic map.
Figure 3	Physical location of markers on the chromosome 7 RH map.
Figure 4	Representative YAC contig map.
Figure 5	Order of STSs in YAC contig maps.
Figure 6	Global positions of the anchored YAC contigs.
Figure 7	Relative resolution of mapped chromosome 7 STSs.
Figure 8	Relationship between genetic and physical distance across the length of human chromosome 7.